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KMID : 0370220110550060451
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Yakhak Hoeji
2011 Volume.55 No. 6 p.451 ~ p.455
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Neuroprotective Activity of So Cheong Ryong Tang with Steaming Process
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Weon Jin-Bae
Yang Hye-Jin
Lee Bo-Hyoung
Yun Bo-Ra
Ma Jin-Yeul
Ma Choong-Je
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Abstract
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So Cheong Ryong Tang (SCRT) has been used as a traditional herbal medicine for the treatment of the bronchial asthma. In this study, the effect of steaming process on changes in 11 major compounds (homogentisic acid, ephedrine HCl, paeoniflorin, cinnamic acid, cinnam aldehyde, glycyrrhizin, 6-gingerol, schizandrin, methyleugenol, gomisin A and gomisin N) content and neuroprotective activity of SCRT were evaluated. Major compound content was slightly different with steaming produce. The contents of paeoniflorin, cinnamic acid, cinnam aldehyde, 6-gingerol and methyleugenol were decreased and homogentisic acid, ephedrine HCl, glycyrrhizin, schizandrin and gomisin A were increased by steaming process. The neuroprotective activity of steaming SCRT was determined in mouse hippocampal HT22 cells by MTT assay. As a result, neuroprotective activity of a steaming SCRT was higher than that of a non steaming SCRT. This study demonstrated that neuroprotective activity of SCRT can be improved through steaming process.
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KEYWORD
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So Cheong Ryong Tang, Steaming process, Major compounds, Neuroprotection
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